DMSO: Nature’s Cure For Just About Everything, You Were Never Meant To Discover

A Historical Glimpse at DMSO

Dimethyl sulfoxide (DMSO), a simple yet potent compound, has a rich history that begins with its discovery by Dr. Alexander M. Saytzeff in 1866. While its initial discovery stirred curiosity, no immediate commercial or medicinal use was identified at the time of its discovery. DMSO remained largely overlooked until the 1950s, when a British scientist recognized its unique Cryoprotective properties—its ability to preserve cells, including bone marrow and blood cells, under freezing temperatures. This discovery opened the door to exploring DMSO's wider applications, particularly in medicine.

In the 1960s, Dr. Stanley Jacob at Oregon Health & Science University Medical School uncovered another groundbreaking property of DMSO: its transdermal abilities. Highly purified DMSO could penetrate skin and organ membranes without causing damage. This discovery sparked new excitement, as DMSO appeared to be a safe and effective means for transporting substances directly through the skin. However, despite promising research and an impressive safety profile, DMSO faced resistance from regulatory bodies, hindering its path to mainstream medical acceptance.

The Medical Mafia and the FDA’s Attack on DMSO

Despite DMSO’s promising properties, the journey to its acceptance has been fraught with controversy. After Dr. Stanley Jacob’s initial findings in the 1960s, which demonstrated DMSO's safe transdermal properties and its potential to address a range of ailments, the medical community was buzzing with excitement. Studies had already been conducted on over 100,000 patients, all of which consistently showed DMSO to be nontoxic, with a unique therapeutic profile.

However, regulatory bodies like the FDA soon cast doubt over DMSO’s potential. Rather than advancing research, the FDA restricted DMSO’s medical use, citing safety concerns that many proponents believe were completely unfounded and possibly even corporate/politically motivated. This pushback led to DMSO being labeled as an unapproved drug (despite it being a completely natural compound found in wood - not a drug) for human use in the United States, despite insurmountable evidence of its effectiveness and safety.

Critics often refer to this resistance as the influence of the “medical mafia,” a term used to describe the political influence of pharmaceutical companies and regulatory agencies that appear to thwart inexpensive and effective treatments. With its wide range of healing capabilities—from reducing inflammation and relieving chronic pain to supporting cellular repair and increasing blood flow —DMSO presented a low-cost alternative to countless pharmaceuticals, making it a potential threat to the pharmaceutical industry’s bottom line.

To this day, while DMSO is widely available and used in veterinary medicine and as a cryoprotectant, its use for human health applications remains limited in the U.S., despite global studies confirming its safety.

Nature’s Cure All - The Unique Chemistry of DMSO

DMSO stands out in the scientific world not only because of its transdermal properties but also due to its unique chemical structure. It is both hydrophilic (water-attracting) and hydrophobic (water-repelling), a rare combination that enables it to dissolve a wide array of substances. This dual nature allows DMSO to penetrate cell membranes and interact with cellular components efficiently. Its versatility as a solvent makes it an invaluable tool for carrying nutrients, medications, and other beneficial compounds directly into cells.

This ability to cross barriers that other substances cannot makes DMSO incredibly effective as a carrier agent. It can transport other compounds through the skin and into the bloodstream, which makes it a powerful vehicle for enhancing the delivery and absorption of medications and supplements.

Additionally, because DMSO can interact with both water and lipid (fat) layers, it integrates smoothly with biological systems. This adaptability gives DMSO its reputation for being not just a treatment in itself, but also a means of delivering a variety of healing agents with greater efficacy.

Major Actions and Therapeutic Benefits of DMSO

DMSO is a remarkable compound with a diverse set of therapeutic effects. Here’s a closer look at each of its key benefits:

• Antimicrobial Properties: DMSO is effective against a broad spectrum of pathogens, including bacteria, viruses, and fungi. It works by disrupting microbial cell walls, which helps prevent infections. This makes DMSO a natural alternative to antibiotics for treating wounds, infections, and other pathogen-related conditions.

• Muscle Relaxant: As a muscle relaxant, DMSO helps to relieve muscle spasms and tightness by penetrating muscle fibers and reducing inflammation at a cellular level. This can bring comfort to those with conditions like back pain, cramps, or muscle stiffness, providing relief without the use of conventional muscle relaxants.

• Boosts White Blood Cells and Macrophages: By stimulating the immune system, DMSO increases the production of white blood cells and macrophages—cells responsible for identifying and destroying harmful invaders. This enhances the body’s ability to fight infections and maintain a strong immune defense.

• Increases Cell Membrane Permeability: DMSO enhances the permeability of cell membranes, making it easier for nutrients to enter cells and for toxins to exit. This is particularly beneficial for detoxification, as it helps remove waste products that can accumulate and cause cellular dysfunction.

• Radioprotective Qualities: Known to protect cells from radiation damage, DMSO acts as a shield against the harmful effects of x-rays and radiation therapy. Its ability to scavenge free radicals generated by radiation can reduce mutations and protect tissues from long-term damage.

• Inhibits Cancer Growth: Research highlights DMSO’s anticancer potential by inhibiting key cell cycle proteins and causing apoptosis (cell death) in cancer cells. DMSO disrupts the CDK2-cyclin A complex, halting cell division, and triggers DNA fragmentation and caspase 3 enzyme activation, potentially sparing healthy cells.

• Cholinesterase Inhibitor: DMSO blocks the action of cholinesterase, an enzyme that breaks down acetylcholine. By preserving acetylcholine levels, DMSO may help improve nerve function and cognitive processes, making it potentially beneficial for conditions involving nerve damage or cognitive decline.

• Effective Heavy Metal Detoxifier: DMSO binds to toxic heavy metals—such as aluminum, mercury, cadmium, arsenic, and nickel—allowing them to be expelled from the body via urine and sweat. This property makes DMSO a valuable tool for detoxification, helping to reduce the body’s burden of harmful metals linked to chronic health issues.

• Pain Relief: Known for its analgesic properties, DMSO blocks the transmission of pain signals along nerves. By interfering with pain pathways, it can provide relief for a range of pain conditions, from arthritis to injuries, without the side effects of narcotics.

• Cryoprotective Agent: DMSO’s ability to protect cells from freezing damage is used in organ and tissue preservation. By preventing the formation of damaging ice crystals, DMSO has applications in organ transplants and biological preservation.

• Bacteriostatic Agent: As a bacteriostatic, DMSO inhibits bacterial growth, helping to control infections. While it doesn’t kill bacteria directly, it prevents their spread, offering a gentle way to manage infections without disrupting the microbiome.

• Diuretic: DMSO has a diuretic effect, which helps reduce fluid retention and swelling. This property is useful in conditions like edema, where excess fluid accumulates in tissues, as DMSO assists in flushing out fluids through the kidneys.

• Anti-Inflammatory: One of DMSO’s most powerful effects is its ability to reduce inflammation by suppressing inflammatory molecules. This property makes it valuable for treating inflammatory conditions, from arthritis to injuries, and promoting faster healing.

• Improves Blood Supply to Injured Areas: DMSO promotes blood flow to damaged tissues by dilating blood vessels and reducing blood thickness. This ensures a better oxygen supply to the cells in injured areas, accelerating recovery and reducing pain from poor circulation.

• Free Radical Scavenger: DMSO neutralizes free radicals—unstable molecules that cause cellular damage and accelerate aging. By scavenging these radicals, DMSO protects cells from oxidative stress, preserving cellular health and longevity.

• Protects Cells from Mechanical Damage: DMSO strengthens cellular structures, allowing cells to withstand physical stress more effectively. It acts faster than many pharmaceuticals to protect tissues, making it an excellent option for post-injury support.

• Calming Effect on the Central Nervous System: Known to ease nervous tension, DMSO has a soothing effect on the central nervous system. This can help in managing stress-related symptoms, bringing a sense of calm without the need for sedative drugs.

• Carrier for Other Drugs and Supplements: DMSO’s ability to transport other compounds through skin and cell membranes makes it a unique carrier agent. It increases the efficacy of medications and supplements, ensuring that more of the active ingredients reach their target areas.

• Nontoxic and Safe: Extensive research on DMSO has shown it to be remarkably safe, with few side effects when used as directed. Its natural compatibility with biological systems means it’s tolerated well, providing a therapeutic option without the toxicity concerns associated with many synthetic drugs.

One last Specific benefit I wanted to separate out From the list is Methylation:

To use DMSO for supporting methylation, the approach generally involves topical application or, in some cases, oral use under professional guidance. Here’s a safe and effective way to consider DMSO use for methylation support:

1. Topical Application: The most common and accessible way to use DMSO for methylation support is through a diluted topical application. Using a 50-70% DMSO solution applied to the skin allows it to penetrate directly into cells and potentially support methylation at the cellular level.

   • How to Apply: Apply a few drops of the diluted solution (e.g., 50-70% DMSO mixed with distilled water) to clean, dry skin, preferably over areas with thin skin, like the inner wrists or forearms. Let it absorb for 15-20 minutes, then rinse off. This can be done 1-2 times daily.

   • Why Topical? This method leverages DMSO’s ability to penetrate the skin and deliver methyl groups to nearby cells without needing to pass through the digestive system.

2. Combining with Other Methyl Donors: To further enhance methylation, DMSO can be combined with a diet rich in methyl-donating nutrients like B vitamins (especially B12, B6, and folate), choline, and methionine. DMSO may help these nutrients reach the cells more effectively when used topically as a carrier.

3. Consultation for Oral Use: Oral use of DMSO is less common and should only be done with guidance from a healthcare provider experienced with DMSO. In specific, low doses, DMSO can help deliver methyl groups systemically, but oral use must be monitored carefully for safety.

By using DMSO in these ways, you can support methylation’s impact on energy, detoxification, and cellular repair in a safe, effective manner. 

Precautions and Usage Guidelines for DMSO

While DMSO is known for its versatility and safety, proper usage is essential to ensure maximum benefit and avoid potential side effects. Here are some important precautions and guidelines for using DMSO:

• Purity Matters: When using DMSO, always choose highly purified medical-grade DMSO, typically 99.9% pure. Lower-purity products may contain contaminants that could be harmful, especially when applied to the skin.

• Dilution for Skin Applications: DMSO is very powerful and can cause skin irritation if applied at full strength. It’s often diluted to concentrations between 50% and 70% for topical use. It’s wise to start with a small patch test on the skin to ensure no adverse reactions.

• Cleanliness is Key: DMSO rapidly penetrates the skin, so it’s essential to apply it to clean skin and with clean hands. Any impurities on the skin’s surface (such as lotions, perfumes, or even dust) can also be carried into the bloodstream.

• Avoid Mixing with Unknown Substances: Given its ability to transport compounds through the skin, avoid combining DMSO with substances that haven’t been tested for compatibility, as they could carry harmful ingredients into the body.

• Storage and Handling: Store DMSO in a cool, dark place away from direct sunlight. It can degrade over time if exposed to light or extreme temperatures, so keeping it in an amber glass bottle is recommended.

How to Use DMSO for Specific Ailments

Dimethyl sulfoxide (DMSO) is a versatile compound with a range of therapeutic applications. Below are detailed guidelines for its use in various conditions, along with references to support each recommendation:

General Precautions:

• Purity Matters: Always use pharmaceutical-grade 99.99% PURE DMSO to ensure safety and efficacy. Industrial-grade DMSO may contain impurities harmful to humans. WebMD

• Dilution for Skin Applications: DMSO can cause skin irritation if applied at full strength. It's often diluted to concentrations between 50% and 70% for topical use. Herbal Mana

• Cleanliness is Key: Apply DMSO to clean skin to prevent the absorption of contaminants. DMSO's ability to carry substances through the skin underscores the importance of cleanliness. Herbal Mana

  For safe and effective use, follow these detailed application instructions for various health issues. These guidelines are based on diluting 99.9% pure pharmaceutical-grade DMSO. Always consult a healthcare provider when trying DMSO for the first time, especially for sensitive applications or internal use.

  Note on Dilution - To create lower concentrations:

  • 70% Solution: Mix 7 parts DMSO with 3 parts distilled water.

  • 50% Solution: Mix equal parts (1:1) DMSO and distilled water.

  • 30% Solution: Mix 3 parts DMSO with 7 parts distilled water.

  • 25% Solution: Mix 1 part DMSO with 3 parts distilled water.

  • 5% Solution: Mix 1 part DMSO with 19 parts distilled water or saline.For safe and effective use, follow these detailed application instructions for various health issues. Always consult a healthcare provider when trying DMSO for the first time, especially for sensitive applications or internal use.

Applications:

• Aches and Pains

  • Application: Mix a solution of 50-70% DMSO with distilled water. Apply a few drops to the sore area, massaging gently. Let it sit for 20-30 minutes, then rinse with water. Use 2-3 times daily for ongoing pain relief.

  • Reference: Studies show DMSO’s efficacy in relieving pain from osteoarthritis (WebMD).

• Burns and Bursitis

  • Application: For burns, use a 50% solution applied with a cotton ball 2-3 times daily, allowing it to absorb. For bursitis, apply a 70% solution to the joint, massaging gently.

  • Reference: DMSO’s anti-inflammatory benefits are valuable for burn and bursitis care (Herbal Mana).

• Carpal Tunnel Syndrome

  • Application: Use a 50% DMSO solution on the wrist area, applying twice daily for 20 minutes.

  • Reference: Research suggests DMSO’s potential in nerve pain relief, such as for carpal tunnel (Herbal Mana).

• Frozen Shoulder

  • Application: A 70% solution can be applied generously over the shoulder joint. Massage in a circular motion and let it sit for 20-30 minutes. Repeat twice daily.

  • Reference: DMSO’s muscle-relaxing properties aid in conditions like frozen shoulder (Herbal Mana).

• Eye Health

  • Application: Dilute to 5% (5 parts DMSO to 95 parts saline). Use 1-2 drops in each eye, twice a week at most, under medical supervision.

  • Reference: DMSO’s application for eye health has shown potential, though caution is critical (Herbal Mana).

• Arthritis

  • Application: Apply a 70% solution to arthritic joints 2-3 times daily, massaging gently.

  • Reference: DMSO’s anti-inflammatory effects make it effective for arthritis management (WebMD).

• Restless Leg Syndrome

  • Application: Use a 50-70% solution on the legs before bedtime, focusing on areas of discomfort.

  • Reference: Though specific studies are limited, DMSO’s muscle relaxation properties can help with restless leg syndrome (Herbal Mana).

• Cavities and Oral Health

  • Application: Swish 1 teaspoon of 25% DMSO solution for 1-2 minutes, then spit and rinse with water. Use once daily.

  • Reference: DMSO’s antimicrobial properties support oral health (Herbal Mana).

• Muscle Repair

  • Application: Mix a 70% DMSO solution with a carrier oil in a 1:1 ratio, massaging into sore muscles after activity.

  • Reference: DMSO assists in muscle recovery due to its anti-inflammatory effects (Herbal Mana).

• Ears and Sinuses

  • Application: For ear issues, apply a 30% solution (3 parts DMSO to 7 parts water) with 1-2 drops twice daily. For sinuses, dab the solution around the nose, avoiding nostrils, and inhale deeply.

  • Reference: DMSO’s anti-inflammatory benefits aid in ear and sinus health (Herbal Mana).

• Hemorrhoids

  • Application: Use a 50% solution applied with a clean cotton ball 1-2 times daily.

  • Reference: DMSO’s anti-inflammatory and analgesic effects reduce hemorrhoid discomfort (Herbal Mana).

• First Aid and Wounds

  • Application: A 50% solution can be applied to minor cuts and wounds with a cotton ball. Let it absorb for 20 minutes, then cover with a sterile bandage. Reapply twice daily.

  • Reference: DMSO’s antimicrobial and healing properties support wound care (Herbal Mana).

DMSO for Pets

• Application for Joint Pain: Apply a 50% DMSO solution to the joint area once daily in pets, massaging gently.

• Wound Care: Use a 30% DMSO solution on pet wounds with a sterile cloth.

• Reference: DMSO is commonly used in veterinary medicine for inflammation and wound care (Herbal Mana).

Note: Always consult a healthcare professional before beginning any new treatment, especially for sensitive applications or internal use.

I would love to hear from you and have you share your thoughts and/or questions in the comment section below. I look forward to hearing your perspectives.

An Invitation:

To truly transform your health and overcome chronic fatigue, chronic disease, and other challenges, it's crucial to uncover advanced health strategies and adopt new, healthy lifestyle habits. Imagine making conscious nutritional choices, creating a chemical-free, non-toxic household for your loved ones, and finding companies that provide products with certifiably safe ingredients. Picture yourself with a structured daily fitness regimen (suitable for all levels of fitness), experiencing deep restorative sleep, and effectively managing stress.

I want to personally invite you to explore the SHIFT ETHOS WELLNESS PATHWAYS PROCESS (Tab at the top of this page or link provided below) – a journey back to true health. Dive deeper into these essential elements and experience a comprehensive approach to wellness by enrolling in this revitalizing process, transforming your life, and embracing a healthier you!

Click here: SHIFT ETHOS WELLNESS PATHWAYS PROCESS, to learn more and consider taking the first step towards revitalizing your health. Schedule a free consult by pressing the blue button at the bottom of the WELLNESS PATHWAYS page.

Disclaimer:

I am not a medical doctor or a medical practitioner. I am not legally permitted to claim I treat, cure, or heal disease. I can, however, provide educational content with respect to building/restoring and maintaining optimal health through nutrition, diet, sleep support, and exercise, which can reverse health conditions.

Any information provided on this site is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this web site.

This website summarizes information on the role of nutrition, diet, and exercise in health, disease and wellness. Readers should be aware that knowledge of nutrition and medicine is constantly evolving. They are encouraged to frequently check the most current information available on preventive and therapeutic measures. It is your designated clinician’s responsibility, relying on their experience and knowledge of the patient, to determine the best course of action in providing care and your choice to follow it or not.

 The author, editor, and publisher of information on this website accepts no liability for any injury arising out of the use of material contained herein, and makes no warranty, express or implied, with respect to the contents of this online publication, or from the contents of sites or articles we provide links to.